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filingDate 2018-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f75b5038c20e97f075a1a5b88cfe8aa
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publicationDate 2021-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3785768-A1
titleOfInvention Target for drug treatment of tumor metastasis and use thereof
abstract Disclosed is a use of PRAK as a drug target in screening a drug for inhibiting or preventing tumor cell metastasis. Based on the discovery that PRAK can be used as a target for tumor cell metastasis, further provided is a drug capable of inhibiting or preventing tumor cell metastasis. The active ingredient of the drug can reduce the expression level of PRAK or inhibit the bioactivity of PRAK, and the inhibition or prevention of tumor cell metastasis can be achieved by regulating the cell migration and the expression and/or function of HIF1α, MMP2 and/or EMT series molecules.
priorityDate 2018-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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