http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3785726-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb8dbd7182ea460f32395c4e0f781ac3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-37 |
| filingDate | 2019-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c258fdecf6c1a11674680d6f26c9c45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03278512d8c0a27977aefe83efc9d87d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0222281513e1f9aff49c93ff6a8c611 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70c843d56d940e8e6456f2611c341178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5814dbd4ca9bb2405f6c1e4de793b263 |
| publicationDate | 2021-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3785726-A1 |
| titleOfInvention | Factor viii protein with increased half-life |
| abstract | The present invention relates to recombinant coagulation factors, in particular, recombinant Factor VIII (FVIII) proteins having an increased half-life. They comprise a heavy chain portion and a light chain portion of Factor VIII and at least two albumin binding domains, wherein at least one albumin binding domain is C-terminal to the heavy chain portion and at least one albumin binding domain is C-terminal to the light chain portion. If the protein is a single chain protein, the albumin binding domain(s) C-terminal to the heavy chain portion is/are N-terminal to the light chain portion. The invention also relates to nucleic acids encoding the proteins of the invention, methods of producing them and pharmaceutical compositions comprising any of these, wherein the pharmaceutical composition preferably is for use in treatment of hemophilia A. |
| priorityDate | 2019-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 214.