| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b8e2017b321a8b2a55f4c091d6b89c0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 |
| filingDate |
2019-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9442bf4a71744fda0e7ad60837bab9d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2fa8bc84d7d67b1a603f16e9b9de9c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6cde014c141aeafc6a426b8a1e65f9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a79e855d808142a7a73a0b875e947f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_624a4efd39a3b0ca6251c629dde05438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_699fd816b9136a2f8fe4caec21636df6 |
| publicationDate |
2021-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3781586-A1 |
| titleOfInvention |
A method for production of high purity icatibant |
| abstract |
The present invention provides a process for the manufacture of peptidomimetic drug icatibant with high yield and purity by fragment condensation on the solid phase. In particular, it describes a convergent synthesis by condensation of a protected C-terminal fragment bound to a solid support and a protected N-terminal fragment, followed by cleavage from the support and resulting in a crude peptide of high purity, which is further purified to obtain pure icatibant in high yield. The invention further provides intermediates useful in the manufacturing process. |
| priorityDate |
2018-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |