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filingDate 2015-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3778867-A1
titleOfInvention Phage resistant lactic acid bacteria
abstract The present invention provides a method for the construction of a bacteriophage-insensitive mutant of a Streptococcus thermophilus parent strain whereby the bacteriophage insensitivity is not based on the CRISPR resistance mechanism but based on another mechanism. The method provides a protocol by which this can be achieved by inactivating one or more of the CRISPR systems present in a given strain. The invention also provides the bacteriophage-insensitive mutants as well as their use in a process for making a dairy product.
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