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filingDate 2019-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56a256e409399febcf008c1b808a10a4
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publicationDate 2021-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3775879-A1
titleOfInvention Selective enrichment of high-quality dna intact sperms from a semen sample
abstract Disclosed is a composition for selective enrichment of progressively motile non-fragmented / intact DNA sperms during swim-up of semen sample comprising combination of electrolytes, a mix of excipients, polyyvinylpyrrolidone, recombinant human serum albumin or bovine serum albumin. A method of selective enrichment of DNA-intact sperms using the compositions of the present invention is also disclosed. The DNA fragmentation index of the swim-up sperms are less than the DNA fragmentation index of the neat samples. The media compositions of the present invention are applicable for enrichment of non-fragmented / intact DNA sperms for therapeutic purposes in the field of assisted reproductive technologies.
priorityDate 2018-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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