http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3768243-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60aa2cfbda65440d1bd3e8b59c17cb25 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-217 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate | 2019-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb23942e44ae7d30527853b084325b1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c3db1a2f9db55c11b2ff0fe76fa9897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71d4c96891bde681761dd914a322ef31 |
| publicationDate | 2021-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3768243-A1 |
| titleOfInvention | Liposomes for targeting tumor-associated macrophages |
| abstract | The invention relates to a composition comprising a liposome comprising a first phospholipid comprising a C 14- C 19 :0 fatty acid and a C 3- C 15 :0 fatty acid with a c-terminal carboxyl or a carboxaldehyde group; a second phospholipid comprising a C 14- C 19 :0 fatty acid and a C 14- C 19 :0 fatty acid and a sterol. The first phospholipid is preferably a phosphatidylcholine. The second phospholipid is preferably HSPC and the sterol is preferably cholesterol. In some embodiments the molar ratio of the respective ingredients is 2-3 : 5-6 : 2-3; preferably respectively 2: 6: 2; or 3: 5: 2. The invention also relates to the use of these composition in the targeting of M2 macrophages. |
| priorityDate | 2018-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.