http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3749287-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_677c37b8ad449440695cbc591cd07eb7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5026 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2846 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28 |
| filingDate | 2019-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b8544034f15e5adcea94b25468fee7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a40cff4483aed434a9b299b9965c63b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b896eecff2d117d9df0a35873ce24b0 |
| publicationDate | 2020-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3749287-A1 |
| titleOfInvention | Pharmaceutical formulation for a solid dosage form of opioid receptor antagonists |
| abstract | The present disclosure provides a sustained release formulation of opioid receptor antagonists comprising a sustained release granule comprising at least one of the opioid receptor antagonist, at least one of pharmaceutical acceptable carrier, and a pH-dependent polymer, wherein the sustained release granule is coated with the pH-dependent polymer, and the opioid receptor antagonist is selected from the group consisting of Nalmefene, Naltrexone, or a salt thereof. The present disclosure further provides a method for preparing a sustained release formulation of opioid receptor antagonists comprising steps of: mixing at least one of the opioid receptor antagonist and at least one of pharmaceutical acceptable carrier to form a mixture; performing a wet granulation on the mixture with a pH-dependent polymer to form a sustained release granule; sieving the sustained release granule through a mesh screen to obtain a sieved sustained release granule; and compressing the sieved sustained release granule to obtain a sustained release (SR) formulation. |
| priorityDate | 2018-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.