| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2397e3a8940955961a101bb6264012f5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-724
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8813
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-067
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-724
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-8665
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-4077 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 |
| filingDate |
2019-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ed49bece9750b9e24acf74785efb6e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd46017f70115b801f2518a539b37e45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06064b21628e6000583cb82f68cbfe61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69559abbe9916b29ffce6317d970a1c4 |
| publicationDate |
2020-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3746781-A1 |
| titleOfInvention |
Methods and systems for detection of vitamin d metabolites |
| abstract |
A method and kit for detecting at least two vitamin D metabolites in a biological sample is disclosed, which comprises processing the biological sample to prepare the sample for LC-MS/MS analysis, passing the prepared sample through a liquid chromatography column having an outlet connected to an inlet port of a tandem mass spectrometer to separate said two vitamin D metabolites, if present in the sample, and introduce the two vitamin D metabolites into the tandem mass spectrometer. The method further comprises generating [M+H]+ ions of each of the two vitamin D metabolites in said tandem mass spectrometer, and generating two fragment ions of said [M+H]+ ions associated with said vitamin D metabolites, wherein said fragment ions are not due to water losses from the [M+H]+ ions; and detecting the fragment ions to identify presence of the two metabolites in the biological sample. |
| priorityDate |
2018-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |