| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5df5ae200801690027bd305c84230d0b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-6054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-599
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2015-8518
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-6081 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0087
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-177
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0638
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-725
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate |
2019-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23d8e50e3a57040a4e5acc40f69a7099
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d15f9d6cd0b51d66cb582a47e79b7465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1afaeaeeadfea6a3a4ea517daf79c742
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6487db4386ecfd53f2d61d3c57163dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0597ec6c11cf60a51b55fef0cf1d86d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ac43b8c2a8cb78317961d4e394ce22c |
| publicationDate |
2020-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3737741-A1 |
| titleOfInvention |
Method for transducing cells with a viral vector for the expression of a chimeric antigen receptor (car) or transgenic t-cell receptor (tcr) |
| abstract |
The present invention provides a method for transducing cells with a viral vector which comprises a nucleic acid encoding a chimeric antigen receptor (CAR) or transgenic T-cell receptor (TCR) against a target antigen, wherein the cells comprise a subpopulation of cells which express the target antigen and a subpopulation of cells which do not express the target antigen, which method comprises the step of transducing the cells at a multiplicity of infection (MOI) such that the subpopulation of cells which do not express the target antigen are transduced to a greater extent than the subpopulation of cells which express the target antigen. The present invention also provides a cell composition made by such a method and their use in the treatment and/or prevention of disease. |
| priorityDate |
2018-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |