abstract |
The present invention relates to novel compounds of formula (I) and pharmaceutically acceptable salts, solvates, salt solvates thereof, useful in prevention (for example, delaying onset or reducing the risk of development) and the treatment (eg, control, alleviation or slowing of progression) of cancer, including glioblastoma, bone cancer, head and neck cancer, melanoma, basal cell carcinoma, squamous cell carcinoma , adenocarcinoma, oral cancer, esophageal cancer, gastric cancer, colon cancer, bladder cancer, hepatocellular carcinoma, renal cell carcinoma, pancreatic cancer, cancer of the ovarian, cervical cancer, lung cancer, breast cancer and prostate cancer. The compounds of formula (I), or their pharmaceutically acceptable salts, are inhibitors of IDO. |