http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3723843-A1

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publicationDate 2020-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3723843-A1
titleOfInvention Systems for clinical effect-based neurostimulation
abstract This document discusses, among other things, systems and methods for delivering electrostimulation to specific tissue of a patient. An example of a system can receive a three-dimensional voxelized model representing a plurality of regions each specified as a target region or an avoidance region. The system includes control circuitry to determine a metric value using the voxelized model. The metric value indicates a clinical effect of electrostimulation on the plurality of regions according to a stimulation current and a current fractionalization. The control circuitry can determine a desired stimulation current that results in a first metric value satisfying a clinical effect condition. The system can generate a stimulation configuration including the desired stimulation current and the current fractionalization corresponding to the first metric value, and deliver tissue stimulation according to the stimulation configuration.
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