| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf8a3231cd88b81a086ffdc933fdef2c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-782 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q17-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4174
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-17023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-4946
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-411
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate |
2018-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12e99806e846ceee2f95ab06ac5b48f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dd13efdf49752336dd1fb3504fdd5a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a8e2ed41011107241e26babb18386bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01fb42928b4269a89ec0b856534450ef |
| publicationDate |
2020-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3717077-A1 |
| titleOfInvention |
Methods for modulating pigmentation by angiotensin-converting enzyme 2 modulation |
| abstract |
The invention relates to a cosmetic method for modulating pigmentation in a subject, comprising administering a modulator of angiotensin-converting enzyme 2 (ACE2 modulator) to said subject. The invention encompasses methods in which the ACE2 modulator is an inhibitor of angiotensin- converting enzyme 2 (ACE2 inhibitor) and the ACE2 inhibitor is administered to increase pigmentation in said subject, in addition to methods where the ACE2 modulator is an activator of angiotensin-converting enzyme 2 (ACE2 activator) and the ACE2 activator is administered to decrease pigmentation in said subject. The invention further relates to the treatment of inflammatory skin disease by inhibition of angiotensin-converting enzyme 2. In some embodiments, the method relates to an inhibitor of angiotensin-converting enzyme 2 (ACE2 inhibitor) for use as a medicament in the treatment of inflammatory skin disease. The invention further relates to corresponding pharmaceutical and cosmetic compositions, preferably suited for topical administration of an ACE2 modulator. |
| priorityDate |
2017-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |