| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d55dd4da0d8f5bfa72abe0507617311d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-307
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-514
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-101
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-501
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-117 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
| filingDate |
2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efad2184a811729f130dd360df71ab02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bc55e6d0f3bca3721351df0f66d6aa1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d1d6867c309b5cf9569cbaacf57c694
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e2ba5f11a20388902810b5870651ef2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9bfd8e78afefa1be2cac1bd7a8cb40e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dda96f85a3ae001c6a780adfce21be6c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0af14e8b082a1932eb826730429f548a |
| publicationDate |
2020-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3710596-A1 |
| titleOfInvention |
Mapping the location, type and strand of damaged and/or mismatched nucleotides in double-stranded dna |
| abstract |
Method comprising incubating a double-stranded nucleic acid having a nick with a nick translating activity, a ligase, and a nucleotide mix comprising at least one modified nucleotide, to generate a product comprising a patch of a newly synthesized strand of a duplex nucleic acid containing a plurality of modified nucleoside monophosphates that are at or adjacent to the site of the nick. The method may also comprise treating the nucleic acid with modified nucleotides with bisulfite or deaminase. In some embodiments, the method may be used to map damaged nucleoside monophosphates in a nucleic acid. Compositions and kits for use in performing the method are also provided. |
| priorityDate |
2017-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |