| abstract |
The invention generally relates to methods and reagents for reducing or stopping lactation in a non-human mammalian subject. In particular, the invention relates to a method of reducing or stopping lactation in a non-human mammal subject by administering to the subject, by intramammary infusion, an agent that activates the signaling pathway by OAS2 or induces the OAS2 expression. In some examples, the methods and reagents of the invention may be useful for the prevention of mastitis in a non-human mammalian subject, such as a dairy cow. |