| abstract |
The present invention relates to novel compounds of formula (I) having a high affinity and a high activity with respect to the α2δ subunit of voltage-dependent calcium channels (VGCCs), in particular the α2δ subunit. -1 voltage-dependent calcium channels or dual activity vis-à-vis the voltage-dependent calcium channel α2δ subunit (VGCC), in particular, the α2δ-1 subunit of calcium channels dependent on the voltage, and the μ-opioid receptor (MOR or mu-opioid receptor). The invention also relates to a process for the preparation of said compounds as well as compositions comprising them, and their use as medicaments. |