Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6f2dfd800f5740a25a62ba57f6c4271 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B2207-114 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-367 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-361 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-0072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B26-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-0032 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B27-0025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-0076 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B21-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
filingDate |
2018-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc9f3ea3a186a202a5c664b3f94e2918 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9148c68bb0965354bf99f0aa40c373e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_714b742e6c8b4212ecf54cae85a57f57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9edeab80c0ff7c5739b1f329455ef20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ef0ba3373a63ae701fe359ba64e5543 |
publicationDate |
2020-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3695263-A1 |
titleOfInvention |
High-resolution, real-time imaging with adaptive optics and lattice light sheets |
abstract |
A microscope directs light through an excitation lens having an axis oriented in a first direction to generate a network light sheet (LLS) within a sample. A detection objective oriented in a direction substantially perpendicular to the first direction collects the signal light emitted by the sample in response to the LLS within the sample and forms an image from the light collected on a detector . A second light beam is imaged on a focal plane of the excitation lens, a third light beam is imaged on a focal plane of the detection lens. One or more wavefront detectors determine a light wavefront emitted from the sample and through the excitation lens in response to the second light beam imaged on the focal plane of the excitation lens and determine a wavefront of light emitted from the sample through the detection lens in response to the third light beam imaged on the focal plane of the detection lens. A first wavefront modulation element modifies a wavefront of the first light beam to reduce sample induced LLS aberration within the sample, and a second wavefront modulation element. The waveform modifies a wavefront of the transmitted signal light in response to the LLS to reduce an aberration of the sample-induced signal light at the detector. |
priorityDate |
2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |