http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3695263-A1

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filingDate 2018-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc9f3ea3a186a202a5c664b3f94e2918
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publicationDate 2020-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3695263-A1
titleOfInvention High-resolution, real-time imaging with adaptive optics and lattice light sheets
abstract A microscope directs light through an excitation lens having an axis oriented in a first direction to generate a network light sheet (LLS) within a sample. A detection objective oriented in a direction substantially perpendicular to the first direction collects the signal light emitted by the sample in response to the LLS within the sample and forms an image from the light collected on a detector . A second light beam is imaged on a focal plane of the excitation lens, a third light beam is imaged on a focal plane of the detection lens. One or more wavefront detectors determine a light wavefront emitted from the sample and through the excitation lens in response to the second light beam imaged on the focal plane of the excitation lens and determine a wavefront of light emitted from the sample through the detection lens in response to the third light beam imaged on the focal plane of the detection lens. A first wavefront modulation element modifies a wavefront of the first light beam to reduce sample induced LLS aberration within the sample, and a second wavefront modulation element. The waveform modifies a wavefront of the transmitted signal light in response to the LLS to reduce an aberration of the sample-induced signal light at the detector.
priorityDate 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 34.