abstract |
The present invention relates to a compound of formula (I), wherein, P 1 , P 3 , P 4 and P 5 are amino acid residues or amino acid related structures. The invention also relates to a compound of formula (I) for use as an inhibitor of caspase-2 and its therapeutic use. The invention further relates to the use of a compound of formula (I) as a basic activity probe for selectively detecting caspase-2 activity. |