| abstract |
Embodiments of the invention include methods and compositions associated with treating or reducing the severity or delaying the onset of one or more heart conditions in a mammal. In particular embodiments, the compositions are directed to Park2 and its use for a cardiac medical condition. In specific cases, effective amounts of Park2 polynucleotide (s) and / or Park2 polypeptide (s) are provided to an individual in need, including for heart failure, for example. Administration can be applied locally to the heart, for example. |