abstract |
The invention relates to compounds having the following structure: [formula] or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, in the formula, R3, L1, L2, G1, G2 and G3 are as defined in the description. The invention also relates to the use of the compounds as a component of lipid nanoparticulate formulations for the delivery of a therapeutic agent, compositions comprising the compounds and methods for their use and preparation. |