http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3661543-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b13f9ae7641c518a3d82ef598ab78910 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-03018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-50 |
filingDate | 2018-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1c88ee29f7bb579da050242f1ddfa62 |
publicationDate | 2020-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-3661543-A1 |
titleOfInvention | Modified ddah polypeptides comprising a pharmacokinetic enhancing moiety, improved pharmacology and their uses |
abstract | The present invention relates to modified DDAH polypeptides and uses thereof. Exemplary embodiments relate to DDAH polypeptides which include one or more amino acid substitutions, additions or deletions by naturally occurring or non-naturally encoded amino acids, and / or binding to other molecules. biologically active agents including other DDAH polypeptides, as well as PKEM. In addition, the use of said DDAH polypeptides for the treatment of a disease, such as heart failure or kidney disease is further described. |
priorityDate | 2017-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1236.