http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3658919-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_54d112629ffe022ebab46c4bee61f80a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 |
| filingDate | 2018-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2302ed24f06d1f145ac0a64e3a008b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe42814b9b717c51dd01dc1b798549a1 |
| publicationDate | 2020-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3658919-A1 |
| titleOfInvention | A method for determining tissue insulin sensitivity, a method for identifying insulin resistance and determining a predisposition for a disorder connected therewith and use of insulin sensitivity index |
| abstract | The object of the present invention is to provide a method for determining tissue insulin sensitivity in a human subject, wherein in a blood sample extracted from a human subject, the following laboratory parameters and the concentrations following proteins in serum are measured: red blood cell count (RBC), alanine aminotransferase (A1AT), peptide C, sex hormone binding globulin (SHBG), adiponectin, insulin-like growth factor binding protein 1 (IGFBP1), and on the basis of the results obtained from the measurement, an index of insulin sensitivity is determined. The subject of the present invention also relates to a method of identifying insulin resistance and determining a predisposition to a disorder related to insulin resistance in a human subject, such as, in a blood sample extracted from a human subject, the following laboratory parameters and the following protein concentrations in serum are measured: red blood cell count (RBC), alanine aminotransferase (A1AT), peptide C, sex hormone binding globulin ( SHBG), adiponectin, insulin-like growth factor binding protein (IGFBP1); and on the basis of the results obtained, an index of insulin sensitivity is determined, insulin sensitivity is identified and a predisposition to a disorder associated with insulin resistance is determined. The subject matter of the invention also relates to an insulin sensitivity index serving as a diagnostic biomarker, serving as a biomarker of insulin resistance, serving as a biomarker for the prognosis of a disorder associated with resistance to insulin resistance. insulin for determining a predisposition to a disorder associated with insulin resistance. The subject of the invention also relates to the use of the insulin sensitivity biomarker for the control of insulin sensitivity of tissues, particularly in a disorder and / or disease connected to the resistance to insulin. insulin, especially type 2 diabetes. |
| priorityDate | 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 675.