abstract |
The present invention relates to a method of protecting the heart from damage by administering to a patient at risk of such damage a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAPĪ², or the expression or the activity of at least one of these molecules. This composition is preferably in the form of a siRNA construct, more preferably an HSR construct, which inhibits the expression of mAKAPĪ². |