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filingDate 2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40e0dc37687ecdf16d6f7a7254bed823
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publicationDate 2020-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3658072-A1
titleOfInvention Device and method of creating a fluid containment field for administering therapeutics to a nerve
abstract According to the invention, a severed nerve can be surgically sutured and several axons fused through sequential administrations of solutions. The solutions may include a primer solution comprising methylene blue in a Ca 2+ free saline solution, a fusion solution comprising about 50% (w / w) PEG, and a sealing solution comprising saline solution. containing Ca 2+ . The PEG fusion solution can be applied in a nerve processing device, designed to isolate the injured segment of the nerve. The device may include a containment chamber for creating a liquid confining field around the anastomosis. The device may include incisions, slits and / or openings in opposite end walls of the device, adapted to receive the nerve. The device may have an open bath configuration or may include separable lower and upper bodies to create a closed bath configuration. The device may include one or more liquid ports in fluid communication with the containment chamber for introducing and / or discharging the liquid.
priorityDate 2017-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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