| abstract |
The present invention provides, inter alia, an antigen-binding antibody or polypeptide that binds or is capable of binding to CD 166, compositions comprising them, and uses thereof. In some embodiments, an anti-CD166 antibody or antigen-binding polypeptide of the present invention binds or is capable of binding to all or part of an intracellular domain ("ICD") of CD166. The invention also includes, inter alia, a nucleic acid molecule encoding an antigen-binding antibody or polypeptide that binds or is capable of binding to CD166. In various embodiments, an anti-CD166 antibody or a polypeptide An antigen binding is useful in a method of detecting or treating a condition or disease. |