abstract |
The present invention relates to pyrrolopyrimidine compounds according to formula (I) and their use in the prophylaxis and / or treatment of pain, inflammatory conditions, cardiovascular diseases, neurodegenerative diseases, neurological diseases, complications of diabetes. type I, cancer and / or fibrotic diseases. In a particular aspect, the present compounds are ASK inhibitors, in particular inhibitors of ASK1. The present invention also relates to processes for producing a compound of the invention, pharmaceutical compositions comprising a compound of the invention, the use of the compounds in the prophylaxis and / or treatment of pain, inflammatory conditions , cardiovascular diseases, neurodegenerative diseases, neurological diseases, complications of type I diabetes, cancer and / or fibrotic diseases. (Formula (I)) |