| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-712
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 |
| filingDate |
2018-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc126694417bb6864a6a7c572e4e610a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4a45ddaa0ef5eaee9c0427774454c42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c98147427c631751666b98d7aebe872
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16f1d3ba12cd9ecb282f45514aa1d625 |
| publicationDate |
2020-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3651774-A1 |
| titleOfInvention |
Incorporation of unnatural nucleotides and methods of usein vivo |
| abstract |
In vivo methods, compositions and kits for producing nucleic acids that include at least one unnatural base are provided. The invention provides in vivo methods for producing a nucleic acid that contains an expanded genetic alphabet, the method comprising incorporating at least one non-naturally occurring base into the nucleic acid. The invention relates to semi-synthetic organisms comprising an expanded genetic alphabet, the genetic alphabet comprising at least one non-natural base. The present invention provides compositions comprising a heterologous or recombinant polymerase and methods of using the same. In addition, the invention provides kits that are useful for stably incorporating non-naturally occurring nucleic acid into a nucleic acid molecule, for example, using the methods provided by the present invention in an in vitro state or in a cell-free state. |
| priorityDate |
2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |