Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebc2bf1056f9c4af593d3b1dd32f8cad |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10322 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10321 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10323 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-235 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
filingDate |
2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7206b25c72d5c3c192688fab757e7ef5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34622fef822f2a29abfca83d9e1f174b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f754404ce2add93a71311a364b898f9 |
publicationDate |
2020-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3649237-A1 |
titleOfInvention |
Non human great apes adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof |
abstract |
The present invention relates to novel adenovirus strains with high immunogenicity and no pre-existing immunity in the general human population. The absence of pre-existing immunity is due to new hypervariable regions of the hexon protein of adenoviral capsid. The new adenovirus strains also have an improved reproductive capacity. The present invention relates to nucleotide and amino acid sequences of these novel adenovirus strains, as well as recombinant viruses, viral-like particles and vectors based on these strains. The invention further relates to pharmaceutical compositions and medical uses in the therapy or prophylaxis of a disease, and methods of producing an adenovirus or viral-like particles using the novel sequences, recombinant viruses, particles viral type and vectors. |
priorityDate |
2017-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |