| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_957fa57076b78a02be642391629b060e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e09319fe979c0d63f50e0b9dcf132ae |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4707
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2018-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be35989bc5539c34eb4d82d0ee4e4f47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_891197cc0faf046dd6eb934bb8499eff |
| publicationDate |
2020-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3648783-A1 |
| titleOfInvention |
Novel polynucleotides encoding a human fkrp protein |
| abstract |
The present invention relates to synthetic polynucleotides encoding a human fukutin-related protein (FKRP), said polynucleotides containing at least one mutation avoiding additional transcript (s) generated from the codon (s) of Frameshift initiation. Said polynucleotides are useful, in particular for the treatment of a pathology related to a FKRP deficiency or induced by a defect in the glycosylation of α-dystroglycan (α-DG), such as LGMD2I. |
| priorityDate |
2017-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |