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filingDate 2019-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3647791-A3
titleOfInvention Srm/mrm assays for notch pathway proteins
abstract Methods are provided for detecting and quantifying the DLL1, DLL3, JAG1, JAG2, Notchl, Notch 2, Notch 3, Notch 4, and/or DLL4 proteins in biological samples, such as a formalin fixed paraffin embedded tissue samples, using mass spectrometry. Additionally, methods are provided for treating cancer based upon the level of the DLL1, DLL3, JAG1, JAG2, Notchl, Notch 2, Notch 3, Notch 4, and/or DLL4 proteins in the biological samples.
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