| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5513
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5517 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-22 |
| filingDate |
2018-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b681583c006923222cf9a21afaca6ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99a4d3faaa7a049b3363e5d94fbff0fd |
| publicationDate |
2020-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3642206-A1 |
| titleOfInvention |
Enhancing gaba's ability to modulate immune responses |
| abstract |
Embodiments of the present invention provide methods of reducing an inflammatory immune response (e.g., inhibition of a Th1 response) and / or ameliorating a regulatory immune response (e.g. improvement of Treg (s)) in a mammal, said methods comprising administering to the mammal a GABAA receptor positive allosteric modulator (PAM) in an amount sufficient to reduce an inflammatory immune response and / or to promote an immune response regulating said mammal. In some embodiments, PAM is co-administered with a GABA receptor activating ligand (eg, GABA). |
| priorityDate |
2017-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |