Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf2c54d5a3e3f639740ecbfbb72fd4b4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2013 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 |
filingDate |
2018-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05414423c108aa9c066b2422c8abbca0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53c8e91edfaa7edcccdd4711364cc85b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_095e7ddc3eb60a59e8f946eac5339369 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de16d0683c8606fcacc90bab5a7c57ae |
publicationDate |
2020-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3641759-A1 |
titleOfInvention |
Orally dissolving melatonin formulation with acidifying agent that renders melatonin soluble in saliva |
abstract |
A composition comprises a pharmaceutical dosage form configured to integrate into saliva and maintain a pH of 4 or less within the saliva during the time when the dosage form is dissolved therein. The dosage form comprises a therapeutically effective amount of melatonin in a carrier matrix, a disintegrating agent, and a sufficient amount of acid to impart pH to the saliva. The amount of the disintegrating agent is sufficient to cause complete disintegration of the dosage form in saliva within ten minutes of contact with saliva. |
priorityDate |
2017-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |