| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d28722ea47feca3df8aff6cabb7f7cf7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0043 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate |
2018-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f5fa5f196ae12cbee89a0b1f371423f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_465e86cc6e1ad824504aaf1e02108467
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e93262cb2310e3a46e8504a663ef35b4 |
| publicationDate |
2020-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3641728-A1 |
| titleOfInvention |
An oil-in-water nanoemulsion composition of clobetasol |
| abstract |
The invention relates to an oil-in-water nanoemulsion composition having a continuous aqueous phase and dispersed oil droplets, the nanoemulsion comprising: (a) clobetasol; (b) one or more oily components; and (c) one or more surfactants; with one or more pharmaceutically acceptable excipients or carriers, wherein: the osmolality of the nanoemulsion is between 100 and 500 mOsm / kg; the average size of the droplets measured by dynamic light scattering is between 1 and 500 nm; the ratio by weight of the oily component to clobetasol is from 1: 1 to 200: 1; and the weight ratio of surfactant to clobetasol is from 2: 1 to 200: 1. Processes for preparing and using said composition as a medicament, and in the prophylaxis and / or treatment of inflammatory diseases or conditions are further described. |
| priorityDate |
2017-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |