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publicationDate 2020-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3638294-A1
titleOfInvention Antibodies capable of binding hla-a2/tyrd in an hla restricted manner and uses thereof
abstract Antibodies capable of binding HLA-A2/Tyrosinase (TyrD) in an HLA restricted manner are provided. Specifically, the antibodies are capable of binding HLA-A2/TyrD369-377 in an HLA restricted manner. Further provided are complementary determining region (CDR) sequences of heavy chain and light chain of antibodies, and methods of using the antibodies for the treatment of cancer.
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