http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3625557-A1

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filingDate 2018-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_718edac40b7a58944ac1a6aa0c2b407e
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publicationDate 2020-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3625557-A1
titleOfInvention Method and apparatus using surface acoustic waves
abstract A method of reducing the limit of detection in a surface acoustic wave sensor (SAW) includes the steps of: attaching a plurality of DNA segments to a detection surface of a SAW; performing a CRISPR/Cas9 preparation of the DNA segments to bind a selected protein into at least one of a plurality of the DNA segments; conjugating a nanoparticle to the selected protein; and measuring the number of DNA segments with conjugated nanoparticles using a surface acoustic wave sensor (SAW). The nanoparticle may be modified to form a single electron transistor (SET) which generates a detectable signal in response to RF or ultrasonic excitation which is indicative of binding of the corresponding nanoparticle to a selected target analyte.
priorityDate 2017-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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