http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3603764-A1

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filingDate 2015-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccbc6efb5786f5d5068f8c8b7dfd2253
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publicationDate 2020-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3603764-A1
titleOfInvention High performance liquid chromatography method for polypeptide mixtures
abstract The present invention relates to a high performance liquid chromatography method for polypeptide mixtures. Specifically, the method including the following steps: step (1): preparing a solution of the glatiramer acetate to be tested; step (2): performing gradient elution on a sample to be tested with a cation exchange liquid chromatography; step (3): determining a peak area corresponding to each component of the glatiramer acetate , comparing the peak area with to a peak area of a reference substance to determine whether the co ntent of each component of the sample to be tested is in a qualified range.
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