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publicationDate 2020-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3597636-A1
titleOfInvention Crystal forms of 3-z-[1-(4-(n-((4-methyl-piperazin-1-yl)-methylcarbonyl)-n-methyl-amino)-phenylamino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone
abstract A plurality of free base crystal forms of 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-phenylamino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone and preparation methods therefor; further provided are the pharmaceutical formulations containing the crystal forms and a use thereof in the treatment of diseases, in particular in the treatment of angiogenic eye diseases.
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