Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac6a3988706950bbdf228437b2faf1cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c666474ffc0184da7e8aafe5f0b324d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-008 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4707 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0075 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864 |
filingDate |
2018-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d28293d15088c36e1d07b17004042370 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acdf94176fa910686cddb7430a6e0ad6 |
publicationDate |
2020-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3596112-A2 |
titleOfInvention |
Adeno-associated virus vector delivery of a fragment of micro-dystrophin to treat muscular dystrophy |
abstract |
The invention provides gene therapy vectors, such as adeno-associated viral vectors (AAVs), expressing a functional fragment of the miniaturized human micro-dystrophin gene as well as methods of using these vectors to express the fragment of micro-dystrophin in skeletal muscles, including the diaphragm and cardiac muscle, and to protect muscle fibers from injury, to increase muscle strength and to reduce and / or prevent fibrosis in subjects with muscular dystrophy. |
priorityDate |
2017-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |