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filingDate 2019-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3591063-A1
titleOfInvention A long chain dibasic acid with low content of long chain dibasic acid impurity of shorter carbon-chain and preparation method thereof
abstract The present invention relates to a long-chain dibasic acid with low content of long-chain dibasic acid impurity of shorter carbon chain, to the preparation of a long-chain dibasic acid producing strain by directed evolution of POX gene and homologous recombination, and to the production of a long-chain dibasic acid with low content of long-chain dibasic acid impurity of shorter carbon chain by using the strain. The present invention also relates to a strain containing a mutated promoter, wherein, when a long-chain dibasic acid is produced by fermentation of this strain, the content of the acid impurity of shorter carbon chain in the fermentation product is significantly reduced.
priorityDate 2018-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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