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filingDate 2013-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3578201-A1
titleOfInvention Methods and compositions for natural killer cells
abstract The application provides new compositions and methods for stimulating the production of natural killer (NK) cells in a subject. NK cells can be selectively expanded with a combination of stimulating ligands. Methods and compositions for the administration of stimulatory ligands modified to self-insert into tumor cells, thereby stimulating an increase in the number of NK cells in proximity to a tumor, are also described.
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