abstract |
The invention relates to a genetically modified microorganism expressing a functional type I or II RuBisCO enzyme and a functional phosphoribulokinase (PRK), and in which the glycolysis pathway is at least partially inhibited, said microorganism being genetically modified such that it produces an exogenous molecule and/or overproduces an endogenous molecule. According to the invention, the oxidative branch of the pentose phosphate pathway can also be at least partially inhibited. The invention further relates to the use of such a genetically modified microorganism for producing or overproducing a molecule of interest, and to methods for the synthesis or bioconversion of molecules of interest. |