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publicationDate 2019-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3573998-A1
titleOfInvention Scn9a antisense pain killer
abstract The current invention provides peptide nucleic acid derivatives targeting the 3' splice site of exon 4 in the human SCN9A pre-mRNA. The peptide nucleic acid derivatives potently induce SCN9A mRNA splice variant(s) lacking the SCN9A exon 4 in cells, and are useful to safely treat pains or conditions involving Nav1.7 activity.
priorityDate 2017-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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