| abstract |
The present invention relates to a monoclonal mouse antibody targeting a unique sialoglycosylated cancer-associated epitope of CD43, produced by the hybridoma cell deposited under ICLC accession number ICLC PD n° 16001. Furthermore, the invention relates to an antibody, comprising a heavy chain variable region comprising complementarity determining regions CDRH1, CDRH2 and CDRH3, and a light chain variable region comprising complementarity determining regions CDRL1, CDRL2 and CDRL3, wherein CDRH1, CDRH2, CDRH3, CDRL1, CDRL2, and CDRL3 comprise the amino acid sequences GFTFSSFGMH, YISSGSGNFYYVDTVKG, STYYHGSRGAMDY, SASSSVSSMYWY, DTSKMAS, and QQWSSYPPIT, respectively. In addition, the invention relates to antibodies recognizing the same epitope. |