| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc18752b143a0edc509fc16ba761a2af |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-552
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_486fa01568c1f2d3457fe8d52aa6bb1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90ca6a9be91a35b3cd46bbcb8dffaf7d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4b7025bf1bb5964e3d6310a8ad05563 |
| publicationDate |
2019-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3542165-A1 |
| titleOfInvention |
Combined assay for the differential diagnosis of the alzheimer's disease |
| abstract |
The invention provides a combined immuno-infrared assay for the differential diagnosis and sub classification of Alzheimer's disease into different disease stages. The method can be applied for assured disease diagnostics and patient stratification. The assay considers the label-free detection of the change within the Amyloid-beta peptide and Tauprotein secondary structure distribution in bodily fluids. This secondary structure change from native to ß-sheet enriched isoforms appears years before clinical disease manifestation. Now, the combined method utilizesthis shift for diagnostics based on liquid biopsies. |
| priorityDate |
2016-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |