abstract |
The invention relates to PUFA, vitamin E, vitamin D and the protein bound amino acids glycine, arginine and tryptophan as active ingredients for use in therapy of patients with sarcopenia and/or frailty or pre-sarcopenic and/or pre-frail patients, wherein an effective amount of said active ingredients is administered in the form of a nutritional composition comprising a) a lipid component providing 40-50 EN% based on the total energy of the nutritional composition, wherein 12-16 EN% based on the total energy of the nutritional composition is provided by PUFA, b) 4.0-8.0 mg/100mL alpha-TE vitamin E, c) 5.0-12.0 μg/100mL vitamin D, d) 2.5-4.5 g/100mL glycine, e) 0.5-1.5 g/100mL arginine, and f) at least 0.02 g/100mL tryptophan. |