Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce93303ef3715576fec2ff4e60770060 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-10043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20034 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
filingDate |
2017-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1c53ef736c7ae5042a004920634183c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8475f37955f8b53900ca3b6c7c4ce608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08014d45e7beea211f5a655ce89e47c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c1215a7a6f209a377774ade8ffe92dd |
publicationDate |
2019-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3534943-A2 |
titleOfInvention |
Replication-deficient arenavirus particles and tri-segmented arenavirus particles as cancer vaccines |
abstract |
The present application relates generally to genetically modified arenaviruses that are suitable vaccines against neoplastic diseases, such as cancer. The arenaviruses described herein may be suitable as vaccines and/or for treatment of neoplastic diseases and/or for the use in immunotherapies. In particular, provided herein are methods and compositions for treating a neoplastic disease by administering a genetically modified arenavirus in combination with a chemotherapeutic agent, wherein the arenavirus has been engineered to include a nucleotide sequence encoding a tumor antigen, tumor associated antigen or antigenic fragment thereof. |
priorityDate |
2016-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |