http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3526603-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3244ba8390b1f290f4ba36389c82488b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-487 |
filingDate | 2017-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e355c7ff71aaef402647a86bdc370d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a1a982ba782940bb0be9db5abe2879a |
publicationDate | 2019-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-3526603-A1 |
titleOfInvention | Nanopore voltage methods |
abstract | A method for sequencing a nucleic acid molecule includes providing a sequencing cell (200) having a nanopore (216) in a membrane (214) that resides over a well (205), a first electrode (202) at a bottom of the well, a second electrode (210) in a chamber (215) above the membrane, and an electrolyte (206, 208) in the well (205) and the chamber (215). The first electrode (202) is configured to facilitate non-Faradaic conduction of ionic current and forms a capacitance with ions in the electrolyte. A first voltage signal (1310) is applied across the first and second electrodes (202, 210), thereby creating a force that moves a nucleic acid molecule in the sequence cell through the nanopore (216). The first voltage signal (1310) increases to compensate for changes in the capacitance at the first electrode (202) during application of the first voltage signal. The method further includes determining signal values measured during the first voltage signal, which correspond to one or more nucleotides in the nucleic acid molecule. |
priorityDate | 2016-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.