http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3511445-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3736654583e60531b7fac435ad82c5f2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 |
filingDate | 2018-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a791e9abc61a18ff956c1a9866f174f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afa12b7600f23df9cd1da4100f19e451 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4013101d68c1fa960d58be4b9bffd889 |
publicationDate | 2019-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-3511445-A1 |
titleOfInvention | System for the assembly and modification of non-ribosomal peptide synthases |
abstract | The present invention pertains to a system for the assembly and modification of non-ribosomal peptide synthases (NRPS). The system uses novel well defined building blocks (units) comprising condensation subdomains. This strategy allows for the efficient combination of assembly units referred to as exchange Units (XU 2.0 ) independent on their natural occurring specificity for the subsequent NRPS adenylation domain. The system of the invention allows for the easy assembly of NRPS having any amino acid sequence of choice, without any restrictions due to natural occurring NRPS units. The system also allows the exchange of natural NRPS building blocks with the inventive XU 2.0 leading to the production of modified peptides. The invention provides the system, their individual exchange units, nucleic acids encoding these units, as well as methods and uses thereof. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3822348-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021094462-A1 |
priorityDate | 2018-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 705.