| abstract |
Disclosed are compounds of Formula (I), Formula (II), Formula (III), and Formula (IV) or salts thereof, wherein R 2 is -OH or -OP(O)(OH) 2 ; and R 1 is defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein coupled receptor S1P 1 , and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease. |