| abstract |
The invention pertains to the use of soluble sodium in the manufacture of a composition or kit of parts for (therapeutically) improving and prolonging blood plasma uridine levels and tissue availability of uridine, and/or for treating or preventing impaired blood plasma uridine levels and tissue availability of uridine, and/or for preventing/treating disorders associated with impaired blood plasma and tissue availability of uridine, in a mammal, preferably a human being, by orally co-administering soluble sodium and uridine in a molar ratio of soluble sodium to uridine of more than 1 : 1, preferably more than 1.5: 1, more preferably more than 2: 1, even more preferably at least 2.5: 1, even more preferably at least 2.8: 1, more preferably 3 : 1 - 15: 1, most preferably 3 : 1 - 10: 1, particularly 3 : 1 - 5: 1. |