| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_690dd3350f58fb5409d6da5ff99be13b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0065 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4704 |
| filingDate |
2017-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd8eb9bc4746b8f34c562cb68291cb9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b9d134c60b8f84678daae60d1f597d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_406709c1a8c9daac4a3832f0f62a21bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75e3c2b37f77540a7438c8adf33ca81b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f448427015f3d5f19fd7f888baed9d75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4219ef1828b86020ac4df3392461cc83 |
| publicationDate |
2019-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3498260-A1 |
| titleOfInvention |
Oral gastroretentive sustained-release pharmaceutical formulation |
| abstract |
The present invention provides a gastroretentive pharmaceutical composition for oral administration with sustained release comprising at least one active ingredient effective in stomach (preferably rebamipide), which further comprises at least one pharmaceutically acceptable auxiliary substance capable of swelling the pharmaceutical composition to density below 1 g/cmat pH between 1.5 and 3.5, at least one pharmaceutically acceptable auxiliary substance capable of ensuring sustained release of the active ingredient, and at least one pharmaceutically acceptable component capable of forming carbon dioxide upon contact with gastric juices.The pharmaceutical composition can be prepared by wet granulation and/or dry homogenization of the active ingredient with the auxiliary substances and components. |
| priorityDate |
2017-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |